Why we recommend

Retinol is powerful stuff, and it can be harsh on your skin. The great thing about Potent Retinol Complex is the way NeoStrata balances the power of retinol with ingredients such as Centella asiatica and hyaluronic acid that minimise irritation to your skin and keep it hydrated. Potent Retinol Complex delivers a medium dose of retinol (0.3%) to promote cell turnover, 4% niacinamide to reduce age spots and wrinkles, and 2% NeoGlucosamine to strengthen the skin barrier.

NeoStrata Potent Retinol Complex

Powerful night serum that minimises skin irritation


NeoStrata Potent Retinol Complex combines retinol with nourishment and hydration for your skin, giving you smoother, fresher-looking skin with the irritation often associated with retinol products. 


  • Delivers the power of retinol without retinol’s usual irritation
  • Stimulates the growth of new skin cells
  • Improves skin texture, brightness, and clarity
  • Visibly minimises age spots
  • Leaves your skin looking soft and radiant


In a study, after 8 weeks of using Potent Retinol Complex once daily, 97% of participants reported their skin was firmer, while 92% said their wrinkles were less noticeable. 92% also stated their age spots or dark spots were fading.

After 12 weeks, 97% of participants reported that their skin tone was more even and that their skin was lifted and less droopy.


Retinol and Retinoids


All Skin Types

    Your skin consists of three main layers: the epidermis on the outside; the dermis below it; and below that the hypodermis, also called the subcutaneous layer. The lower part of the epidermis constantly generates new skin cells, pushing older cells in the upper layers of the epidermis to the surface, where they eventually die. These dead skin cells form a protective layer, but they can also make your skin uneven and dull-looking.

    Potent Retinol Complex harnesses the power of retinol to speed up your skin’s natural turnover of cells and encourage your body to boost its production of collagen, the vital protein that provides the scaffolding and structure for your skin. This increase in collagen production helps to make fine lines and wrinkles less visible, while niacinamide reduces the prominence of dark spots. At the same time, Centella asiatica nourishes your skin, and hyaluronic acid hydrates it.


    Use Potent Retinol Complex once or twice a week to begin with, preferably in the evening, and gradually work up to daily use as your skin develops its tolerance for retinol.

    To use, cleanse your skin, and then apply Potent Retinol Complex to it.

    In the mornings, apply sunscreen to protect your skin against UV and other light rays.

    Aqua (water), Pentaerythrityl Tetraethylhexanoate, Glycerin, Caprylyl Methicone, PPG-15 Stearyl Ether, Niacinamide, Stearyl Alcohol, Cetearyl Alcohol, Acetyl Glucosamine, Butylene Glycol, Ceteareth-20, Isohexadecane, Cellulose, Retinol, Centella Asiatica Leaf Extract, Citric Acid, Ascorbic Acid, Sodium Hyaluronate, Bisabolol, C13-14 Isoparaffin, Glyceryl Dilaurate, Laureth-7, Polysorbate 20, Caprylyl Glycol, Steareth-10, Ammonium Acryloyldimethyltaurate/ VP Copolymer, Polyacrylamide, Disodium EDTA, Sodium Hydroxide, Xanthan Gum, Phenoxyethanol, Chlorphenesin

    Why should I use Potent Retinol Complex only once or twice a week at first?

    When you begin using any retinol product, start slowly to prevent irritation occurring. Retinol requires a two-stage conversion – first from retinol to retinal, then from retinal to retinoic acid – so it may take two to three days for your skin to show the full effects of Potent Retinol Complex. If you apply a second dose too soon, you may irritate your skin and get symptoms such as sensitivity, dryness, redness, or peeling skin. Instead, start with once or twice a week and give your skin time to build up its tolerance to retinol before gradually working up to daily use.

    Why do I need to wear sunscreen when I’m using a retinol product?

    Retinol typically thins down the outer layer of your skin, which makes it more sensitive to ultraviolet (UV) radiation, so you need to protect your skin against burning. Use broad-spectrum sun protection any time you’re exposed to UV. That’s not just when you’re actually in the sun, but also in overcast conditions or when you’re exposed to strong light through a window. Alternatively, cover up with sunproof clothing.