Why we recommend
This cream is specifically designed to help you get the most ‘bang from your buck’ from your retinol (an anti-ageing hero ingredient), while minimising irritation. That’s due to the gentle-yet-effective version of retinoid that has been chosen, teamed with peptides and a clever delivery system that gets the ingredients to where they can be most effective in your skin.
Vital Assist Skincare Proliferate + Renew Cellular Renewal Cream
Line-reducing cream with retinol and growth factors
This wrinkle-reducing cream uses two of skincare’s biggest hero ingredients – retinol and peptides – plus patented delivery technology, to visibly reduce signs of skin ageing with less irritation. From fine lines and wrinkles to dark spots, Vital Assist Skincare Proliferate + Renew Cellular Renewal Cream works by stimulating your skin’s natural collagen production, leading to a firmer, smoother complexion.
PRIMARY BENEFITS
- Contains a potent combination of retinoids and peptides
- Helps to stimulate your natural collagen levels to smooth and plump your skin
- Treats fine lines, wrinkles, and dark spots
- Reduces irritation due to patented skin delivery system
CATEGORY
Peptides and Growth Factors and Retinol and Retinoids
SKIN TYPE
All Skin Types
- How it Works
- Ingredients
- FAQ
Vital Assist Skincare Proliferate + Renew Cellular Renewal Cream contains Glyceryl Diretinoate (abbreviated to GDR), an advanced retinoid that encourages cell turnover and a healthier complexion when the naturally occurring enzymes within your skin convert the GDR into Retinoic Acid, the active form of Vitamin A.
GDR is joined in the formula by cutting-edge peptides that also encourage your fibroblast cells to produce more collagen, and extensive laboratory testing has shown that the concentrations of retinoid and peptides in the cream can achieve optimal anti-ageing results.
These active ingredients are delivered deeper into your epidermis – while producing less irritation – due to a patented lipid-encapsulation delivery mechanism, called Selective Enzyme Release Technology (SERT). This means you benefit from a slow release of the retinoid directly to the target cells.
HOW TO USE IT
Apply cream after cleansing and your treatment step if you are using one. Introduce gradually and apply sparingly.
Warnings: For external use only. If irritation occurs, discontinue use. Avoid contact with eyes. Keep out of reach of children.
DI Water, Glyceryl Stearate SE, Butyrospermum Parkii (Shea) Butter, Glycerin, C12-15 Alkyl Benzoate, Cetyl Alcohol, Dimethicone, Butylene Glycol, Phospholipids, Myristoyl Nonapeptide-3, Retinol, Glyceryl Diretinoate, Retinol Linoleate, Lysophosphatidic Acid, Ascorbyl Linoleate, Glabridin, Cholecalciferol, Ethyl Macadamiate, Allantoin, Passiflora Edulis Seed Oil, Passiflora Incarnata Seed Oil, Panthenol, Tocopheryl Acetate, Linoleamidopropyl PG-Dimonium Chloride Phosphate, Propylene Glycol, Carthamus Tinctorius (Safflower) Seed Oil, Caprylyl Methicone, Polysilicone-11, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Cetearyl Alcohol, Steareth-20, Steareth-10, Polysorbate 80, Steareth-21, Steareth-2, Fragrance, Caprylyl Glycol, Phenoxyethanol, Tromethamine.
What is retinol?
Retinol is a derivative of vitamin A and one of the most researched ingredients in skincare for wrinkles and uneven skin tone. It works by increasing cell turnover and by stimulating collagen production. Over time, it can improve the appearance of fine lines, pigmentation, uneven texture, and acne. While powerful, it can also cause dryness or irritation – especially when first introduced – so it’s best to use it with care and build up slowly.
What are peptides?
Peptides are short chains of amino acids – the building blocks of proteins like collagen and elastin. In skincare, they act as signaling molecules, triggering the skin to produce more of these structural proteins. The result: firmer, smoother, and more resilient skin. Peptides also help support the skin barrier, reduce inflammation, and improve hydration levels, making them an excellent choice for sensitive or ageing skin.
How to avoid irritation from retinoids?
Retinoids can cause irritation, especially during the initial adjustment phase. To minimise this, always start slow, beginning with a lower-strength retinoid and building up your usage from 1–2 times per week. You can also reduce your side effects by buffering your retinol by applying a moisturiser beforehand, and using hydrating ingredients to support your skin barrier. Don’t forget, retinoids increase sun sensitivity, so daily broad-spectrum sunscreen is essential too.






